I have been researching novel pheromone-like compounds by finding compounds with high affinities for VN receptor cells and it seems like Fasedienol has a high affinity (EC50 = 200 nM), which seems quite a bit higher than current pheromones. It may be effective at 3-20mcg based on information available.
I may be able to source and list this molecule so let me know if you are interested.
Any knowledge about this compound is appreciated.
:-[
(https://i.ibb.co/Ss9gwFw/2024-05-21-17-53.png)
Note: In one study where they used intranasal dosing at 0.8-1.6mcg, there was a significant amount of anxiolysis achieved. Intranasal dosing will of course be more direct, so the amount used should be multiplied for it to be effective.
I was able to acquire PH94B from an outfit in Ukraine called pglchem. They ship to the US.
Still testing it.
I know of PGLChem, I did not know they have PH94B in stock, thanks.
Quote from: greedware on May 21, 2024, 11:31 PMI was able to acquire PH94B from an outfit in Ukraine called pglchem. They ship to the US.
Still testing it.
Very interesting. I'm glad some of us are still pushing the boundaries of pheromone research. What have you noticed so far? Any self effects?
Quote from: greedware on May 21, 2024, 11:31 PMI was able to acquire PH94B from an outfit in Ukraine called pglchem. They ship to the US.
Still testing it.
I'm gonna bump this one more time since I'm real close to pulling the trigger on this. Have you noticed any effects on yourself or others? Is it worth picking up?
It actually appears that M3X contains lots of fasedienol. Thundr says here (https://pherotruth.fans/Thread-Any-success-with-the-new-M3X?action=nextnewest) that M3X contains:
1. E.none
2. 4,16 androstadienol
3. Alpha nol
4. Beta nol
5. DHEA
4,16 androstadienol=fasedienol
I wonder if it's this molecule that's responsible for the disinhibition people report. Does the anti-anxiety effect manifest itself as disinhibition?
Quote from: Mr Level1 on Sep 08, 2024, 10:49 AMQuote from: He-Mone on Aug 25, 2024, 10:53 AMIt actually appears that M3X contains lots of fasedienol. Thundr says here (https://pherotruth.fans/Thread-Any-success-with-the-new-M3X?action=nextnewest) that M3X contains:
1. E.none
2. 4,16 androstadienol
3. Alpha nol
4. Beta nol
5. DHEA
4,16 androstadienol=fasedienol
I wonder if it's this molecule that's responsible for the disinhibition people report. Does the anti-anxiety effect manifest itself as disinhibition?
Did you order some too? I'm trying to check if it's worth to order some myself.
I haven't yet. I lost some of my enthusiasm after I realized it's probably more common in blends than I realized. I always assumed that the "androstadienol" being used by companies like PXS and True Pheromones refered to 5,16 androstadienol, the naturally occuring form, and that 4,16 androstadienol was proprietary to Vistagen pharmaceuticals. But now I'm guessing that companies are referring to the 4,16 form in general. I'd still like to get my hands on some at some point, but the pglchem stuff is low dose and must be water-based if they expect you to spray it up your nose.
Chris from Alpha Dream had this to say about the difference between 4,16 and 5,16 androstadienol:
"In terms of commonly known pheromones, 4,16-androstadien-3b-ol is definitely the one that shines. It is referenced with emphasis in the original Erox patent, and later studies by Erox show it to have a similar response (in mV) to androstadienone when measured using an EVG (electrovomeronasogram)"
Quote from: He-Mone on Aug 25, 2024, 10:53 AMIt actually appears that M3X contains lots of fasedienol. Thundr says here (https://pherotruth.fans/Thread-Any-success-with-the-new-M3X?action=nextnewest) that M3X contains:
1. E.none
2. 4,16 androstadienol
3. Alpha nol
4. Beta nol
5. DHEA
4,16 androstadienol=fasedienol
I wonder if it's this molecule that's responsible for the disinhibition people report. Does the anti-anxiety effect manifest itself as disinhibition?
I wonder if this is P83.
I believe dbot said he thinks the 5, 16 version is TAA.
I
Quote from: invenom on May 21, 2024, 12:37 PMI have been researching novel pheromone-like compounds by finding compounds with high affinities for VN receptor cells and it seems like Fasedienol has a high affinity (EC50 = 200 nM), which seems quite a bit higher than current pheromones. It may be effective at 3-20mcg based on information available.
I may be able to source and list this molecule so let me know if you are interested.
Any knowledge about this compound is appreciated.
:-[
I am interested as I believe this may be a contender for P83.
Thundr's notes on 4, 16:
"My notes on it:
Wear it around girls. Makes them very "hands on".
It works fine in the single digit mcg range.
Slight relaxed mood uplift. (like the good mood chill feeling you get after orgasm)
Can enhance fun during exciting events.
Makes sex a bit more freeky deeky.
Short half life
works synergistic with A-nol heavy mixes
I think its a precursor to A-nol and is higher up on the conversion chain but directly under neno"
https://pherotruth.fans/Thread-Androstadienol--13535 (https://pherotruth.fans/Thread-Androstadienol--13535)
LP on beta-androstadienol:
"It seems like most of the male phero blends out there are geared towards being the alpha dude, conquering the competition, scoring, dragging girls off by their hair... Ok, that's all good, but don't you just love it when you have your big teddy bear all to yourself, your head on his shoulder in front of the TV... drowsy, comfortable and snuggly? Mmmmm...totally sexy!
Did you know there's actually a pheromone for that? It's called beta-androstadienol and it is excreted by the "Alpha Male at Peace". It relaxes both women and men, is said to lessen the symptoms of PMS in women, and makes us feel dreamy, soothed and secure.
We've added this to a set of bonding and subtle sexual arousal pheromones for the perfect cuddly, sensual, experience."
https://lovepotion.invisionzone.com/profile/1-potion-master/content/page/239/?type=forums_topic_post (https://lovepotion.invisionzone.com/profile/1-potion-master/content/page/239/?type=forums_topic_post) (under Teddy Man)
From Tish/NBully:
"beta-androstadienol
This one NBully tested out.
Quote:
Androstadienol is the -Androstenol version of the famous molecule Androstadienone. Androstadienone is found to increase comfort in women. Beta-androstadienol has some reports of being a fun (hilarity) molecule.
I know its a low number in the putatives, somewhere below P85 . I was given the indicatio it is a popular putative. When Nbully asked him on PT he said most of use al ready have it."
https://pherotruth.fans/Thread-Pheromones-by-chemical-name (https://pherotruth.fans/Thread-Pheromones-by-chemical-name)
Quote from: ebbnflow on Sep 23, 2024, 01:21 AMLP on beta-androstadienol:
"It seems like most of the male phero blends out there are geared towards being the alpha dude, conquering the competition, scoring, dragging girls off by their hair... Ok, that's all good, but don't you just love it when you have your big teddy bear all to yourself, your head on his shoulder in front of the TV... drowsy, comfortable and snuggly? Mmmmm...totally sexy!
Did you know there's actually a pheromone for that? It's called beta-androstadienol and it is excreted by the "Alpha Male at Peace". It relaxes both women and men, is said to lessen the symptoms of PMS in women, and makes us feel dreamy, soothed and secure.
We've added this to a set of bonding and subtle sexual arousal pheromones for the perfect cuddly, sensual, experience."
https://lovepotion.invisionzone.com/profile/1-potion-master/content/page/239/?type=forums_topic_post (https://lovepotion.invisionzone.com/profile/1-potion-master/content/page/239/?type=forums_topic_post) (under Teddy Man)
4,16-androstadienol isn't endogenous, so either they are selling 5,16 or the person who wrote the blurb is confusing the two.
Quote from: Mr Level1 on Sep 26, 2024, 03:39 AMQuote from: He-Mone on Sep 26, 2024, 12:26 AM4,16-androstadienol isn't endogenous, so either they are selling 5,16 or the person who wrote the blurb is confusing the two.
Good to stay sharp. These small differences in moleculair structures can make big difference in what they do.
I also read about molecules on drugs fora, to see if there's something interesting for olfactorian use. Did you know that lactic acid and GHB are almost the same in structure? Still your body reacts quite differently to the both...
Well both generally cause horniness or at least are related in that area.
Quote from: Mr Level1 on Sep 27, 2024, 06:32 AMQuote from: KingTaco on Sep 27, 2024, 05:06 AMWell both generally cause horniness or at least are related in that area.
Is that so? I didn't try GHB, after that I saw a friend making it. Those ingredients didn't say: 'drink me' to me... Though I heard people got quite horny from it.
Lactic acid is something your body makes in the proces of sing carbs for energy. (That's why people who do intense sports can get heavy legs.) I'm not sure if it gets anyone horny.
it seems im confusing lactic acid with something else. Yes GHB does make you horny, altough i must admit i never tried it. I do know its used a lot with the 40+ scene in clubs and swingercafes.
Quote from: Mr Level1 on Sep 27, 2024, 02:11 PMQuote from: KingTaco on Sep 27, 2024, 07:43 AMit seems im confusing lactic acid with something else. Yes GHB does make you horny, altough i must admit i never tried it. I do know its used a lot with the 40+ scene in clubs and swingercafes.
No worry, as long as you don't ingest substances without knowing what it is.
I stood right next to the proces of making ghb (the cooking, as people call it) and after seeing what went in, I passed for putting the end result in my body. I know it's a process of bases and acids, but the ingredients were not very appealing.
Anyhow, enough other fun stuff to take. Today my order of rc's came in, for example.
I ve seen people get messed up by RC's. Be careful of the dosages. Sometimes that stuff is stronger than expected.
Quote from: Mr Level1 on Sep 28, 2024, 07:17 AMQuote from: KingTaco on Sep 28, 2024, 03:22 AMI ve seen people get messed up by RC's. Be careful of the dosages. Sometimes that stuff is stronger than expected.
Thanks for the warning.
I can rest you assure. I have quite some experience with substances. I know how to find my information from the most reliable websites. And I know (online and in real life) people who can help me to get the right dosing.
And these are called rc's, but are actually discovered quite some time ago, described in PIKAHL, and tested by a lot of people over the years. It's just called rc's so they can (could) be sold legal. One of them was actually the favorite of Ann Shulgin, the wife of Alexander Shulgin.
When it comes to rc's, my brother is the chemist. I know little of them.
I know more about organic stuff